Epistane Chemical Information
CAS No.: 4267-80-5
Appearance: White Crystalline Powder
Place of Origin: China
Method of Analysis: HPLC
What are the different names/ways of writing Epistane?
The nomenclature for Epistane can be written two different ways, 2a,3a-epithio17a methyl-17b-hydroxy-5a-androstane or 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol. Epistane has also been referred to as Methepitiostane, Epi, Epi 2a3a, and the most common misspelling is Epistain.
What is Epistane?
Epistane is a DHT derived prohormone that was brought to market with their product “Havoc.” Epistane is an anti-estrogenic dry compound that will aid users in adding lean muscle mass as well as cutting fat. In addition to this, Epistane does not aromatize and is non-progestagenic. This basically means that while on Epistane, estrogen related side effects like gyno and progesterone related side effects like sensitive breast tissue are virtually non-existent. Users will experience little to no side effects while on Epistane, making it an ideal beginner prohormone.
The dosage of Epistane
Most people using Epistane for the first time seems to be around 30-40mg per day. Epistane is commonly offered in 10mg capsules and has an average half life. To optimise an Epi cycle we would recommend splitting the dosage evenly. For a 30mg per day Epi cycle – 1 capsule upon waking and another 7 hours later and the final 7 hours later again. For example, if you woke at 7am the dosages would be 7am, 2pm, 9pm using the above method.
For those using 40mg of Epi we would recommend splitting the dosages the same. However, to accommodate the additional 10mg of Epi we would recommend taking this with the first dosage or approximately 1 hour prior to training on training days.
The Effects of Epistane
Methepitiostane/Epistane is an orally active compound derived from dihydrotestosterone. Due to Epistane being orally active no conversion is required to illicit its muscle building effects. Many claim that Epi has anti-oestrogen effects whilst others repudiate the notion. At Anabolic Addictions we side with the notion that Epi DOES have anti-oestrogenic effects. Why? Any meaningful research will lead you to know that Epistane is a c17-alpha alkylated analog of ‘epitiostane’ (note the name ‘epitiostane’ is reflective of methepitiostane ‘meth’ of course denoting the methylated addition). It’s only logical to agree that Epi has anti-oestrogen effects given that the non-methylated analog ‘mepitiostane’ is used clinically for its inherent anti-oestrogenic effects. As such a degree of anti-oestrogenic effect is reasonable to assume in the methlated analog Epistane. As such an anti-oestrogen is not necessary when running an Epi cycle and gyneocomastia (gyno) is of minimal concern, even with sensitive individuals.
Furthermore, since oestrogen is the main culprit for water retention, bloat and fat gain the anti-oestrogenic effect from Epi means it is a prohormone which offers a high quality look to the physique. Thus Epi is a very favourable prohormone to use during cutting phases with a calorie restricted diet. However, Epistane is also noted to greatly increase the rate of protein synthesis and adds to strength gains which means it can equally be used to add lean muscle mass without the addition of unwanted fat and subcutaneous fluid retention. Epistane is an extremely versatile prohormone suitable for both bulking cycles and cutting cycles.
Post Cycle Therapy
Although a SERM PCT is often the most effective and cost efficient PCT option it is accepted that Epi is a viable choice for an OTC PCT if a SERM is unavailable or you would prefer not to use such medications. We feel that stacking Arimistane (Erase) and D-Aspartic Acid (D-AA) offers one of the most complete OTC PCT options for any Epi cycle. The stack is designed to reduced oestrogen and increases natural testosterone levels whilst also helping to reduce cortisol levels, which if unchecked can lead to increased body fat levels and reduced gains.