1. CAS NO.: 112809-51-5
2. Molecular Formula: C17H11N5
3. Molecular Weight: 285.31
4. White or light yellow crystal
5. Usage: Used as API in Treatment of breast disease.
Letrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.
1. Letrozole is for FDA-approved use.
Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.
2. Letrozole is for Off-label uses
Letrozole has been used for ovarian stimulation by fertility doctors
Letrozole is sometimes used as a treatment for gynecomastia, although it is probably most effective at this if caught in an early stage (such as in users of anabolic steroids)
Letrozole has also been shown to delay the fusing of the growth plates in mice
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